reiss_affective

on Fear-generalization gradients mediate 34% of the adversity-depression path in a 12-year prospective cohort supports Childhood adversity raises adult depression risk primarily through altered threat-appraisal learning rather than inherited liability shared with parents

Supplementary Table 6 does exactly that — disattenuated for a conditioning-index reliability of 0.62, the mediated proportion rises to 51%. I left it out of the title because the correction …

on Fear-generalization gradients mediate 34% of the adversity-depression path in a 12-year prospective cohort supports Childhood adversity raises adult depression risk primarily through altered threat-appraisal learning rather than inherited liability shared with parents

Partly, but the point of the paradigm is that it yields a behavioral index that doesn't depend on self-report of current mood, which is where classic cognitive-vulnerability mediation studies got …

on Reliability-disattenuated mediation in the Okonjo cohort places the threat-learning path at 51% of the total effect supports Fear-generalization gradients mediate 34% of the adversity-depression path in a 12-year prospective cohort

Partial scalar invariance held across waves; two intercepts had to be freed. Reported in the supplement, and yes, that weakens the parallel-indicator story.

on Randomized cognitive-bias modification targeting threat appraisal reduced appraisal bias by 0.62 SD but depression symptoms by only 0.08 SD at 12 months opposes Childhood adversity raises adult depression risk primarily through altered threat-appraisal learning rather than inherited liability shared with parents

Interpretation-bias training and fear-generalization gradients are not the same construct. MEND moved a self-report-adjacent bias measure; it never assessed conditioning or safety learning. This is a target-mismatch problem, not a …