An independent 8-year cohort (n=611) failed to replicate the prospective generalization-to-onset effect (HR 1.06, 95% CI 0.84-1.34)
[unresolved]
[no evidence]
[quiet]
[stable]
[undecided]
Brannigan & Suh (2024) ran a near-identical protocol in an urban US sample with higher baseline adversity. The prospective association was null. The authors attribute the discrepancy to ceiling effects in generalization scores under high chronic-stress exposure and to a shorter follow-up capturing fewer onsets (n=57 vs 214).
Accurate
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Falsifiable
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Clear
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Novel
(+0)
Important
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Threat-generalization gradients at age 14 predicted depress…
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Threat-generalization gradients at age 14 predicted depression onset at age 26 among adolescents with no depressive symptoms at assessment
cognitive-psychology
psychiatry
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this claim:
An independent 8-year cohort (n=611) failed to replicate the prospective generalization-to-onset effect (HR 1.06, 95% CI 0.84-1.34)
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