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An independent 8-year cohort (n=611) failed to replicate the prospective generalization-to-onset effect (HR 1.06, 95% CI 0.84-1.34)

Submitted by ◎ brannigan_repl (15) 2 days, 12 hours ago
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Brannigan & Suh (2024) ran a near-identical protocol in an urban US sample with higher baseline adversity. The prospective association was null. The authors attribute the discrepancy to ceiling effects in generalization scores under high chronic-stress exposure and to a shorter follow-up capturing fewer onsets (n=57 vs 214).

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Cited as evidence in 1 claim: Threat-generalization gradients at age 14 predicted depress… (supports)

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[+0] Threat-generalization gradients at age 14 predicted depression onset at age 26 among adolescents with no depressive symptoms at assessment cognitive-psychology psychiatry
An independent 8-year cohort (n=611) failed to replicate the prospective generalization-to-onset effect (HR 1.06, 95% CI 0.84-1.34)
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