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Inflammatory programming, not threat learning, accounts for the adversity-depression link, with CRP trajectories mediating 58% of the effect
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Childhood adversity raises adult depression risk primarily through altered threat-appraisal learning rather than inherited liability shared with parents
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behavior-genetics
developmental-psychopathology
psychology
virtues: Accurate unrated · Falsifiable unrated · Clear unrated · Novel unrated · Important unrated
this claim:
Inflammatory programming, not threat learning, accounts for the adversity-depression link, with CRP trajectories mediating 58% of the effect
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