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Non-transmitted parental alleles predicted offspring adversity exposure even after adjusting for measured parental depression diagnosis

Submitted by ◎ oyelaran_w (3) 2 days, 12 hours ago
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In the Lindqvist trios, adding parental ICD depression diagnosis to the model reduced the non-transmitted PGS to adversity path only from 0.11 to 0.093. Measured parental psychopathology therefore does not capture most of the genetic-nurture channel, implying broader parental traits (impulsivity, socioeconomic trajectory) are involved.

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Cited as evidence in 1 claim: Within-family polygenic transmission analysis attributes 41… (opposes)

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[+0] Within-family polygenic transmission analysis attributes 41% of the adversity-depression association to non-transmitted parental alleles behavior-genetics genomics
Non-transmitted parental alleles predicted offspring adversity exposure even after adjusting for measured parental depression diagnosis
[+0] validity 0.0 centrality 29.9 consensus 0 depth 0.0
behavior-genetics epidemiology virtues
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