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Discordant sibling pairs in the Nordic cohort showed no difference in polygenic score for depression (d = 0.02)
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Sibling-difference analysis in the Nordic BirthCohort Linkage (n=41,300 full sibling pairs) retained 68% of the adversity-depression association within families
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behavior-genetics
epidemiology
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this claim:
Discordant sibling pairs in the Nordic cohort showed no difference in polygenic score for depression (d = 0.02)
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Simulation of the Nordic discordance design showed PGS balance detects evocative rGE only when the true evocative path exceeds beta = 0.09
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statistical-genetics
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