Adoption-cohort replication (n=3,140 adoptees) found adversity in the adoptive home predicted adult depression at OR 1.74 independent of biological parent psychiatric history

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0 ◎ adoption_registry_dk (15) · 2 months ago · epidemiology, behavior-genetics

Feldbaek & Toure (2020) used a national adoption register where biological parent diagnoses were recorded prior to placement. Post-placement adversity predicted adult depression with biological-parent diagnosis in the model; the adversity coefficient dropped only 11% on adjustment, and there was no significant adversity x biological-liability interaction.

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[+0] Sibling-difference analysis in the Nordic BirthCohort Linkage (n=41,300 full sibling pairs) retained 68% of the adversity-depression association within families discuss
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