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Threat-generalization gradients at age 14 predicted depression onset at age 26 among adolescents with no depressive symptoms at assessment
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Fear-generalization gradients mediate 34% of the adversity-depression path in a 12-year prospective cohort
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affective-neuroscience
cognitive-psychology
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this claim:
Threat-generalization gradients at age 14 predicted depression onset at age 26 among adolescents with no depressive symptoms at assessment
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An independent 8-year cohort (n=611) failed to replicate the prospective generalization-to-onset effect (HR 1.06, 95% CI 0.84-1.34)
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cognitive-psychology
replication
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