← back to claim Fear-generalization gradients mediate 34% of the adversity-depression path in a 12-year prospective cohort

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[+0] Childhood adversity raises adult depression risk primarily through altered threat-appraisal learning rather than inherited liability shared with parents discuss [i] behavior-genetics developmental-psychopathology psychology
Fear-generalization gradients mediate 34% of the adversity-depression path in a 12-year prospective cohort
supports (2)
[+0] Reliability-disattenuated mediation in the Okonjo cohort places the threat-learning path at 51% of the total effect discuss [i] psychometrics
[+0] Threat-generalization gradients at age 14 predicted depression onset at age 26 among adolescents with no depressive symptoms at assessment discuss [i] 1 more psychiatry
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