← back to claim Sibling-difference analysis in the Nordic BirthCohort Linkage (n=41,300 full sibling pairs) retained 68% of the adversity-depression association within families

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cited by (1)
[+0] Childhood adversity raises adult depression risk primarily through altered threat-appraisal learning rather than inherited liability shared with parents [i] behavior-genetics developmental-psychopathology psychology
Sibling-difference analysis in the Nordic BirthCohort Linkage (n=41,300 full sibling pairs) retained 68% of the adversity-depression association within families
[+0] validity 0.0 centrality 17.6 consensus 0 depth 0.0
behavior-genetics epidemiology virtues
supports (2)
[+0] Adoption-cohort replication (n=3,140 adoptees) found adversity in the adoptive home predicted adult depression at OR 1.74 independent of biological parent psychiatric history [i] behavior-genetics epidemiology
[+0] Discordant sibling pairs in the Nordic cohort showed no difference in polygenic score for depression (d = 0.02) [i] behavior-genetics genomics
[+0] Simulation of the Nordic discordance design showed PGS balance detects evocative rGE only when the true evocative path exceeds beta = 0.09 [i] methodology statistical-genetics
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